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Image Search Results
Journal: In Vivo
Article Title: Protective Effect of Exercise Training Against Age-induced Cerebral Microvascular Rarefaction: VEGF/Flk-1/PI3K/Akt Signaling and GLUT1 Expression
doi: 10.21873/invivo.14247
Figure Lengend Snippet: Microvessel density and tissue perfusion in the brain of AC, SC, and ET groups. (A) Representative immunohistochemical staining images of brain sections with GLUT1 antibody, delineating the boundaries of microvessels. Magnification 100×; scale bar=50 μm. (B) Percentage of GLUT1-positive area, determining microvessel density. (C) Regional CTP at the cortical surface, measured using a laser Doppler probe through the cranial window. (D) Correlation analysis of regional CTP and microvessel density in the three groups (r 2 =0.8122, p<0.0001). Data are mean±SEM. One-way ANOVA with Tukey’s post hoc test was used. ***p<0.001, ****p<0.0001 vs. AC, respectively; # p<0.05, ### p<0.001 vs. SC, respectively. AC: Age-matched control group; SC: sedentary control group; ET: exercise-trained group; GLUT1: glucose transporter-1; CTP: cerebral tissue perfusion.
Article Snippet: Sections were then incubated with primary antibody,
Techniques: Immunohistochemical staining, Staining, Control